This is pure speculation, but in looking at this long seal from Mohenjo-daro [M-1271], and seal signs from Mesopotamia which we know the meaning of, it could just be that some of the Indus signs are also names of places or of particular cities.
Answer to question 52. from our panel of leading ancient Indus archaeologists.
The research carried out in Sindh during the last forty years, and the study of the chipped stone assemblages stored in Karachi University collections, show that Late (Upper) Palaeolithic [50,000-10,000 years ago] complexes are known from at least five regions of Sindh. Most sites are located close to good quality raw material outcrops and freshwater sources.
Bridget Allchin, a pioneering woman archaeologist of South Asia, recently passed away. The Guardian has a fine summary of her remarkable career.
Wikipedia defines a paleo-channel as "a remnant of an inactive river or stream channel that has been filled or buried by younger sediment.
This is a very important book by two scholars who have spent years studying ancient Mesopotamian cultures (Steinkeller, Harvard University) or leading explorations of more recently discovered Gulf Arab cultures (Laursen, Moesgaard Museum Denmark).
"The weights are precisely made, well polished and systematic (though unfortunately not inscribed with any Indus characters, which would have helped scholars to decipher the script's numerical system)."
A really nice and well-written blog entry about the analysis of bones and other material from ancient Dilmun [Bahrain], before we even knew where the civilization lay.
Geoffrey Bibby was a Cambridge-educated oil executive, who got caught up, against-all-odds, with the tiny Danish Prehistoric Museum of Aarhus, with barely any resources, that nonetheless has emerged as a powerhouse in ancient Dilmun studies, thanks in part to Bibby's initial efforts.
"The most important crafts were in the fields of textiles, ceramic manufacturing, stone carving, household artefacts such as razors, bowls, cups, vases and spindles, and the production of jewelry, statuettes, figurines and children's toys, some of which were mechanical in function."